I created a little script that set the correct time outs:
mscstimeoutsonvsphere.ps1:
import-module failoverclusters
get-cluster | fl *subnet*
(get-cluster).SameSubnetDelay = 1000
(get-cluster).SameSubnetThreshold = 10
(get-cluster).CrossSubnetDelay = 2000
(get-cluster).CrossSubnetThreshold = 10
get-cluster | fl *subnet*
Source:
Microsoft Cluster Service (MSCS) support on ESXi/ESX (1004617)
Guidelines for Microsoft Clustering on vSphere (1037959)
Change List:
# V1.0 Begin
# V1.1 Added Some New Options 12-10-2014
# V1.2 Added Hyper-V Best Practise & NTFS Partition Offset
# V1.3 Added KB2995145 .NET Framework 4.5 garbage collector heap Fix
# V1.4 Added Set Minimum Disk Space Warning level (180GB Default CU6 200GB CU5)
# V1.5 Added Some new features
# V1.6 Changed the Layout & Add Move Arbitration Mailbox
# V1.7 Added PST Export & KB2990117
# V1.8 Added Full backup, Database in GB and Mailbox Size in GB Export CSV
# V1.9 Added Outlook AnyWhere & SafetyNetHoldTime
# V2.0 Added Check DatacenterActivationMode, Get-DatabaseAvailabilityGroupNetwork, Add Static Route, Disable Replation Network on DAG, Database Copies Per Volume (AutoReseed)
# V2.1 Added Edge Subscription
# V2.2 Added Check Transaction Log Growth
# V2.3 Changed the Menu to Submenu’s
# V2.4 Added Check Database White Space
# V2.5 Added MAPI HTTP External URL
# V2.6 Fixed OWA Virtual URL & HTTP URL
# V2.7 Added Fixes & Mountpoints & Changed Set Minimum Disk Space Warning Level from REG to GlobalOverride
# V2.8 Maintaince Added
# V2.9 Set Power to Highperformance
# V3.0 Check of Microsoft.Exchange.Management.PowerShell.SnapIn is loaded
# V3.1 Added Set-OutlookProvider -Identity EXPR -CertPrincipalName msstd:*.domain.com & Set-OutlookProvider -Identity EXCH -CertPrincipalName msstd:*.domain.com
# V3.2 VMware Best Practises & Fixed soms things
Download: https://gallery.technet.microsoft.com/scriptcenter/Configure-Exchange-2013-e0ffb2a6
I thing i see at many client’s where i come is. Enable Automatic scavenging of stale records is forget to enable. This is a best practise. See: https://technet.microsoft.com/nl-nl/library/ff807390(v=ws.10).aspx
Use the Microsoft Best Practice Analyzer 
Powershell 
Set-DnsServerScavenging –ScavengingState $True –RefreshInterval 7:00:00:00 –NoRefreshInterval 7:00:00:00 –ScavengingInterval 7:00:00:00 –ApplyOnAllZones –Verbose